he three scientists study DNA repair mechanisms due to the won 2015 Nobel Prize in Chemistry

　　

The Royal Swedish Academy of Sciences announced Monday, will be awarded the 2015 Nobel Prize in Chemistry Swedish scientist Tomas Lindahl, American scientist Paul Maud Creek and with the United States, of Turkish nationality scientist Aziz Sancar, in recognition of their genes repair mechanism of their contributions.
　　
　　

Statement of the award selection committee released the same day, said the research results winners at the molecular level describe how cells repair genes and maintenance of genetic information for the scientific community to provide basic knowledge on living cells function, some of which are found can be applied to new anti-cancer therapy research and development.

Jury's attention, because the human gene daily UV radiation, carcinogens by the damaging effects of free radicals and, even without these external "attack", intramolecular gene is not stable, a group of thousands of genes can be naturally occurring variations per day . In addition, the human body are making millions of cell divisions per day, defect may occur when a gene is copied. Nevertheless, the human genetic material has not disintegrated, it is because a molecular system capable of monitoring and repair genes play a role.

Lindahl telephone connection at the scene said that the Nobel Prize was surprised that he first participate in this study because we know that cells are damaged gene is inevitable, it must be repaired, so the research is in the field of gene repair important. He said that research in this field is expected for the majority of cancer patients to bring the gospel to bring more hope for the anti-cancer therapy.



　　

Gene scientists working on the field has also been awarded the Nobel Prize several times, October 7, 2009, the University of Cambridge scientists Venkatraman Ramakrishnan (left), American scientist Thomas A. Steitz ( in) and Israeli scientist Ada Yonath for "ribosome structure and function research" and shared the 2009 Nobel Prize in Chemistry.

Like a living body is extremely complex and sophisticated equipment, different "parts" in different positions perform their duties, methodically. All this would be due if the chemical plant life plays the role of engineers 'ribosome': it translated DNA carried by a password, and produce different proteins, each controlling a different body chemical processes.



　　
DNA (deoxyribonucleic acid) is a type of nucleic acid molecules containing deoxyribose by name. Each organism cells. DNA is the genetic material basis of almost all living organisms, it stores a lot of "instructions" of information that can guide the development and functioning of organisms vital functions. But in the living body, the instructions contained in DNA is like a password filled with drawings, only with the ribosome translation, each instruction to get clear and unambiguous execution.
　　
　

Based on the relevant outcomes of ribosome research, it can be easily understood, if the bacterial ribosome function is suppressed, then the bacteria can not survive. In medicine, it is the use of antibiotics to inhibit bacterial ribosomes thereby treating the disease. The jury said the three scientists to build a three-dimensional model to show how different antibiotics is to inhibit ribosome function, "These models have been used to develop new antibiotics, directly help alleviate human pain, save lives."

Among them, Thomas A. Steitz and Ada Yonath in 2014 together with a number of Nobel laureates attend the 5th International DNA and genomic biological activities Week and Jane Austrian Gu Gu ceremony.



　　
　　
　　In 2011 the Second International DNA section, said Austrian Group chairman Chen Yuqi Get Jane Austrian nucleic acid to • Thomas Steitz.
　　

2014 Fifth International DNA and Genome Week, the Nobel Prize winner, Dr. Ada • Yue Nate do "from DNA to protein folding: Ribosomal channel" speech.

Zhen-Ao Group since its inception in 1996, in China for the first time nucleic acid health products into homes of ordinary people, said Austrian excellence in the field of development and application of nucleic acid has also attracted 24 Nobel scientist said Austrian visit, they not only again Jane brings to the Austrian world's most cutting-edge information and research, but also set off a round of upsurge love life and worship of science. Jane Austrian dedicated people of science is also due to have witnessed "24 Nobel scientist" rather shiny.